FROM FASTING TO FAT RESHAPING: EXPLORING THE MOLECULAR PATHWAYS OF INTERMITTENT FASTING-INDUCED ADIPOSE TISSUE REMODELING

From fasting to fat reshaping: exploring the molecular pathways of intermittent fasting-induced adipose tissue remodeling

Obesity, characterised by excessive fat accumulation, is a complex chronic condition that results from dysfunctional adipose tissue expansion due to prolonged calorie surplus.This leads to rapid adipocyte enlargement that exceeds the support capacity of the surrounding neurovascular network, resulting in increased hypoxia, inflammation, and insulin

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Seeking Mechanism Improvement of Optimum Prices for New Services in Long-Distance Trains through Use of Nonlinear-in-the-Parameter Analysis Models of Price Elasticity of Demand

There is discussed usage pattern of the nonlinear-in-the-parameter economic SLA and mathematical models aimed at increase in efficiency of price elasticity of demand analysis mechanism and search of optimum fees for services of railway passenger transport within the solving framework of profitability management problems.Based on the qualitative cha

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Productive wetlands restored for carbon sequestration quickly become net CO2 sinks with site-level factors driving uptake variability.

Inundated wetlands can potentially sequester substantial amounts of soil carbon (C) over the long-term because of slow decomposition and high shield primary productivity, particularly in climates with long growing seasons.Restoring such wetlands may provide one of several effective negative emission technologies to remove atmospheric CO2 and mitiga

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A comprehensive review on green synthesis of titanium dioxide nanoparticles and their diverse biomedical applications

Metal oxide nanoparticles (NPs) have found a variety of applications in numerous industrial, medical, and environmental fields s, attributable to recent advances in Pedometers And Scales the nanotechnology field.Titanium dioxide nanoparticles (TiO2-NPs) have gained importance as metal oxide NPs due to their potential in various fields, particularly

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Antibody Mediated Rejection and T-cell Mediated Rejection Molecular Signatures Using Next-Generation Sequencing in Kidney Transplant Biopsies

Recently, interest in transcriptomic assessment of kidney biopsies has been growing.This study investigates the use of NGS to identify gene expression changes and analyse the pathways involved in rejection.An Illumina bulk RNA sequencing on the polyadenylated RNA of 770 kidney biopsies was conducted.Differentially-expressed genes (DEGs) were determ

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